Prof. Daniel A. Heller

Prof. Daniel A. Heller

Professor of Pharmacology, Weill Cornell Medicine, Cornell University, USA

Profile

 

ACADEMIC HOST

Gray Faculty of Medical & Health Sciences

Saul J. Farber Distinguished Lectures in Medicine
Academic Year 2026/2027

Education

  • B.A. in History, Rice University, Houston, Texas (2000)
  • Ph.D. in Chemistry, University of Illinois at Urbana-Champaign (2010)
  • Postdoctoral Fellow in Biomedical Engineering, Massachusetts Institute of Technology (2010–2012)

Professional Experience

  • Professor, Department of Pharmacology, Weill Cornell Medicine, Cornell University (2022–present)
  • Professor, Physiology, Biophysics & Systems Biology Graduate Program, Weill Cornell Medicine, Cornell University (2022–present)
  • Co-Director, The Pat and Ian Cook Doctoral Program in Cancer Engineering, Memorial Sloan Kettering Cancer Center (2023–present)
  • Member, Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center (2022–present)
  • Graduate Field Faculty, Meinig School of Biomedical Engineering, Cornell University (2021–present)
  • Faculty Member, Center for Molecular Imaging & Nanotechnology, Memorial Sloan Kettering Cancer Center (2012–present)
  • Associate Professor, Department of Pharmacology, Weill Cornell Medicine, Cornell University (2018–2022)
  • Assistant Professor, Department of Pharmacology, Weill Cornell Medicine, Cornell University (2012–2018)
  • Damon Runyon Fellow, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (2010–2012)
  • Postdoctoral Research Associate, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (2010)
  • Researcher, Visigen Biotechnologies, Houston, Texas (2002–2003)
  • Visiting Scientist, Rice Quantum Institute, Rice University (2002–2003)

Research

  • Cancer nanomedicine and targeted drug delivery
  • Nanotechnology and chemical biology
  • Carbon nanotube-based nanosensors and imaging
  • Molecular imaging and detection of cancer biomarkers
  • Nanomedicine for cancer and kidney diseases
  • Development of nanoscale platforms for precision medicine

 

Faculty

Medicine

Selected Publications
  • “Nanosensor-Based Monitoring of Autophagy-Associated Lysosomal Acidification In Vivo,” Nature Chemical Biology (2023)
  • “P-selectin-targeted nanocarriers induce active crossing of the blood-brain barrier via caveolin-1-dependent transcytosis,” Nature Materials (2022)
  • “Detection of ovarian cancer via the spectral fingerprinting of quantum-defect-modified carbon nanotubes in serum by machine learning,” Nature Biomedical Engineering (2022)
  • “A Perception-Based Machine-Perception Nanosensor Platform to Detect Cancer Biomarkers,” Science Advances (2021)
  • “Targeted Drug Delivery Strategies for Precision Medicines,” Nature Reviews Materials (2021)
  • “Harnessing Nanotechnology to Expand the Toolbox of Chemical Biology,” Nature Chemical Biology (2021)
  • “Tumor-specific PI3K inhibition via nanoparticle delivery in head and neck squamous cell carcinoma,” Nature Communications (2017)
  • “P-selectin is a Nanotherapeutic Delivery Target to the Tumor Microenvironment,” Science Translational Medicine (2016)
  • “Nanomedicines for Kidney Diseases,” Kidney International (2016)
  • “Mesoscale Nanoparticles Selectively Target the Renal Proximal Tubule Epithelium,” Nano Letters (2015)
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